It is just another symptom of the system that makes affordable housing rare, not the root issue.

Self-Hosting GitHub is available under the name “GitHub Enterprise”, but there is nothing stopping a smaller company from getting an “Enterprise” license. At my job we are running self-hosted GitHub for less than 50 developers.

Your comment seems needlessly inflammatory, almost aggressive. I did not vote on it at all, but I would not be surprised if the downvotes you received were mostly because of that and not due to disagreement with your points.

“being weird, rude and cringy is their whole thing” does not make that thing any less weird, rude and cringy.

About comments:

Please please please, do not always write comments. Try to write code that does not need comments whenever possible. Proper variable, class and method names go a long way. If you think a block of code needs a comment, turn it into a method and give it a proper name instead.

Comments should be a last resort for cases where making the code self explanatory is not possible, and those should be rare.

About optimization:

Optimal code is code that fulfills it’s purpose without observable issues.

If you try to make something faster without any prior complaints or measurements indicating that it being slow is an actual issue, you are not optimizing, you are just engaging in mental masturbation.

TL;DR: Looks promising in mice, not tested in humans yet.

Should probably point to https://neurosciencenews.com/vaccine-alzheimers-23722/