I think the person who thought I was an AI explained it quite well. Thet said they just got jaded. However, they believed me when I told who I was and apologised. I appreciate it when people are able to revise their idea and it shows they did not have bad intentions.

I would not say people are crazy, there is a lot of manipulation going on on the internet by businesses and some governments. I think a lot of people fall for bots all the time. For example, Twitter and Reddit is full of them. So, I do not think it is that weird that people sometimes are not sure whether they are talking to AI.

What happened to you when you even showed pictures of yourself and they still were convinced you were AI is quite extreme. I hope that that does not happen too often, because that seems like the other person is either a troll or paranoid.

Thank you, I appreciate that very much. I try to be accepting of other ideas and to be understanding. But sometimes it is difficult for me too. Especially if I get many negative reactions and I do not completely understand why (I do not mean you, but some of the other people that responded to me). Then I get defensive as well, even though I try not to be.

Your work sounds nice and very useful! As a researcher, I know a lot about a very small set of subjects. Sometimes, I am wondering whether I am actually contributing enough and whether what I am doing is actually useful. When you are building homes, at least it is very clear who you are helping and how they benefit from it. I would not be able to do it. I have two left hands, as we say in my language. I am not good with the practical stuff, I am only good with theory.

In any case, thank you for the discussion. I checked the gut microbiome out a little bit already and there is a lot of scientific work on it. Very complex and very interesting! I am looking forward to delving into that. I hope you have a nice day (or evening depending on the time where you are).

I am not an AI. I am not sure how to prove that, but I am not. I am a scientific researcher, but in another field than the medical field. Maybe my scientific background shows in the way I communicate? Also, English is not my native language, so that might be why I sound different as well.

The reason I checked out so much research on obesity (as well as on being underweight) is that many of my family members suffer from eating disorders. I lost my little sister to anorexia a couple of years ago and my mother had it. However, some of my family members are obese as well, also due to eating disorders. I think trying to understand why people eat in a certain way and to help them instead of just judging them, might change things. And for me, scientific work and data is the best way to understand things. Maybe that gives you a bit of understanding where I am coming from and why I am interested in this subject.

If something is the result of research, it cannot just be called bullshit and set aside. It is not just another opinion that you can just decide to disagree with, considering the care that usually has been taken to reduce bias and ensure validity. Of course, research can be wrong and it is important to have a scientific debate. However, such a debate should be based on clear reasoning and arguments and other research results.

I was not pitying you. I was being compassionate. There is a difference between the two. I tried to be kind and understanding. That’s all.

Edit: I also wanted to mention that the study I linked refers to a study on women who were pregnant during the famine in WWII in the Netherlands. Maybe that is what you meant.

Thanks for the name. I will check out Rhonda Patrick and see what research I can find on the topic. I thought you were calling the different theories bullshit, but maybe I misunderstood you and you only meant to say that they sound like that. If that is the case, I apologize. I got so much negativity just for mentioning the research that I might have responded too harshly.

I am sorry to hear that you are struggling with weight so much. I think obesity has to do with eating habits. However, there is a reason for why you have this eating habits. One reason for that could be gut microbiome.

What often happens is that people just get angry with themselves for eating too much. And that anger might help in the short term to force yourself to eat less, but in the long term it will not work and it will just make you feel bad about yourself. However, if you look at the actual underlying causes, such as gut microbiome or setpoint theory, this might provide the insight needed for long term weight loss without the extent of suffering that most obese people have to endure.

It is the only study I know about this. I checked it out, because I have a lot of people with anorexia in my family as well as some people with eating disorders causing obesity. I thought maybe being anorexic and pregnant is similar for your body as being in famine and pregnant. So, that is why I know about this study.

That something sounds like bullshit does not mean that it is bullshit. I mean, I believe we should look at the data and the research. I did hear something about the role of gut bacteria but it was more about issues like depression. Might be interesting to check out further. Thank you.

I am not saying people should not fight their cravings. But the cravings of someone who is obese might be very different from someone who has a normal weight. Like I said, if you get below the setpoint often appetite will go up. Considering that most obese people are not able to lose significant weight in the long term, these cravings seem to be too strong and it seems to make people unable to “just eat less”. So, we need a solution for that.

I am not sure whether this is what you are referring to, but I know about this study that says that prenatal exposure to famine in early gestation increases the risk of obesity.

The fat storage cells definitely play a role as well. One of the ways in which the mechanism I discussed works is via leptin, as leptons regulate energy expenditure. Leptin is primarily produced by adipocytes. So, I believe that is where the connection is. This paper says some interesting stuff about it: https://doi.org/10.1242/dmm.008698.

The issue that I was discussing is that most people do not succeed with keeping the weight off. Most obese people do not manage to lose significant weight in the long term as they tend to regain the weight. We need to look at why that is to solve it. The research on setpoints offers at least a partial explanation. However, if you know about research that further explains this, I would be very interested. (Some sources if you are interested: https://pubmed.ncbi.nlm.nih.gov/17469900/, https://pubmed.ncbi.nlm.nih.gov/11684524/, https://pubmed.ncbi.nlm.nih.gov/19175510/)

No being obese is not healthy. It is clearly associated with many health risks. I have no idea why you would infer that I would think it is healthy from what I have said. Obesity is clearly a problem. However, to solve it, I think we should look at the mechanisms behind it and try to understand it. So, that is what I am trying to do.

Saying that something is “just fat people bullshit” is also not a good argument. Maybe we can leave the emotions and especially the anger out of it and just look at the research. You seem angry and I have no idea what I have done to you to make you angry. I just tried to discuss some research on this subject.

No, it is not junk science. Research about it is published in many serious scientific journals. Just check out Scopus or something. You cannot say that it is junk science just because you do not like the results.

You also seem to not understand it. It does not say that you can escape the law of physics. It also does not say that in my explanation. It says that you energy expenditure goes down if you get below the setpoint. So, eating less becomes less effective. At the same time, you appetite will go up. This makes it very difficult to maintain the weight loss and this is why many people fail to keep the weight off in the long term.

Criticism of any research is possible, of course. However, just saying it is junk and misrepresenting what the theory actually says are not good arguments.

If you disagree, then what is your explanation of why most obese people tend to not keep more than 10% weight off over time without medication or surgery? What scientific evidence is there for that? I would be very interested in hearing about alternative research on this topic.

When you are overweight, it is not a case of just eating less. Eating less has very different physical and psychological effects for someone who is overweight than for someone who is not.

If you are interested in learning something about this, you can check out the setpoint theory of body weight. In short, the body has a setpoint for which weight it should be. If you are overweight, this setpoint is at a higher weight than if you are not. If your weight gets below the setpoint, your metabolism will slow down and your appetite will go up and the body starts to try and do everything to go back to this higher weight. That is why most people are not able to lose more than 10% of their weight in the long term. Often, when they gain the weight back, they gain back even more than they lost and the setpoint might even go up further. It is a neverending struggle for most people. Medication like Ozempic affect this mechanism so it becomes possible to lose weight.

If you want, you can find a lot of scientific papers about this. There is quite a lot of research on this and the setpoint theory is well accepted within the medical field specialised in dealing with weight problems, I believe.

In addition, Ozempic is not only a fat loss medicine. It is also used by people with diabetes to lower their glucose.

I think Fairphone is pretty repairable. It is also quite durable. I have had it for years now and dropped it very often, but it hasn’t broken yet.

I actually agree with this. This technology should be open. I know that there are arguments to keep it closed, like it could be misused, etc. However, I think that all the scary stories about AI are also a way to keep attention away from the fact that if you have a monopoly on it, you have enormous power. This power will grow when the tech is used more and more. If all this power is in the hands of a commercial business (even though they say they aren’t), then you know AI is going to be misused to gain money. We do not have clear insight in what they are doing and we have no reason to trust them.

You also know that bad actors, like dictatorial governments will eventually get or develop the technology themselves. So, keeping it closed is not a good way to protect it from that happening. At the same time, you are also keeping it from researchers who could investigate how to use and develop it further to be used responsibly and to the benefit of humanity.

Also, they relied on data generated by people in society who never got any payment or anything for that. So, it is immoral to not share the results with that same people in society openly and instead keeping it closed. I know they used some of my papers. However, I am not allowed to study their model. Seems unfair.

The dangers of AI should be kept at bay using regulation and enforcement by democratically chosen governments, not by commercial businesses or other non-democratic organisations.

I have a mother who used to act like she hated me a significant amount of time until a few years ago. I have a father who does not think I am that important. I used to think both of my parents hate me, or did not love me at least. I now have a more nuanced view of that. They are just people who are very damaged and almost handicapped in certain aspects. In any case, I think I might be able to understand your situation at least a little bit.

For me the most difficult part was not deciding whether to keep in touch with them or not. I mean, that is a very difficult decision and if your father is still hurting you, you should protect yourself. However, for me the most difficult thing is dealing with the damage.

I am not sure if this damaged you in the same way it damaged me. But if it did, I want to tell you that it is not your fault. Your father acting like he hates you is not because of anything you did and certainly not because of who you are. It is because of who he is.

A lot of children who are not loved or who are even hated by their parents think it is their fault. They think something is wrong with them and they deserve it. I mean, that makes sense, right? If it is your fault, then at least the world still is a fair place. And if something happens to a bad person you do not need to be compassionate, so you do not have to deal with any pain you are too little to be able to deal with. Also, you depend on your parents, so you cannot get too mad at them or leave. From the logic of a child, this makes sense.

And it works, it helps you survive. But once you get older, you keep thinking in the same way. You have a very low opinion of yourself and feel like there is something wrong with you or as if you are worthless. And to keep living in this way is familiar, you know you can survive that. You do not know whether you can survive the pain you suppressed all those years. Or it might still be so suppressed that you cannot even feel it. Until one day, it becomes too much and you start thinking that you might want a different life. You might not just want to survive, but actually live.

You do not discuss your mother. If you have a mother that was able to show you love, that might have had a protective effect. I hope so. But if you recognise this story in any way at all. I think it is import for you to know that it is not about accepting that your father hates you. It is about accepting that you are someone that did not deserve this. And that is very painful, but going through the pain of it, is the only way not to feel that anymore. It will free you from it and enable you to live more than survive.

It is a very difficult thing to do. I myself have not yet been able to go through the pain fully. It often feels too overwhelming, too much. However, after each small step I make, I already feel a little bit more free. I really think this is the way to cope with it. At least for me. It might help you as well maybe if you have similar feelings.

Edit to say that therapy can help a lot with this process. Others have said this as well, but I agree with them.

I have this and I have CPTSD. However, I am sure that there can be other causes as well.

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I can understand that it feels that this is the maximum you can cope with. But as long as you keep breathing, you still exist and you can cope. I can promise you that if you go through it instead of around it, it will get better. I cannot promise you exactly when or how high the peaks will be, but I can promise you that as long as you keep breathing you can cope.

My little sister died from anorexia, I had a miscarriage, my parents emotionally neglected and emotionally abused me as a child and several other traumatising stuff happened. I know pain. I do not underestimate yours. But this is how I dealt with it and I think it will help you too.

I sincerely feel for you. But the pain has a function. You need it to process and you need to feel it to eventually be able to make a new and happy life for yourself. Just keep breathing and go through the waves. I know you can do it.

Don’t drink. Cry. It sounds stupid, bit crying out all the pain might help. Do not run from it. Go through it and cry again if you need to. If you can do so safely, drive and scream in the car. Or break some stuff that you do not need anymore (like plates or something).

I have been through some traumatising stuff and the only thing that helps is not to run, but to go through it. I promise you, there will be a peak in pain and then it will reduce and the next peak will be less severe. This will go on and the pain will become less and less. As long as you keep breathing, you can handle it.

Me too.

You actually found it. I was too lazy, bit I still wanted to know. Thanks!

Here it does a great job of reducing a text of 174 words to 172 words. 👍

(I do not want to complain too much. Usually it works and it is short enough for me to quickly read it.)

I can understand what you mean to say, I think. For example, cognitive behavioral therapy aims to change the way in which people suffering from depression think in order to cure them. It can be quite effective. However, in many cases with major depression different therapies, trauma treatment or medication is also required. In the worst cases, someone might need electroshocks.

I think the issue is that people with depression and people with eating disorders often get blamed for it and they often blame themselves. They are legitimately ill and it is not their fault, just like having any other condition is not your fault. However, due to society’s message of ‘just say no’ to depressive thoughts or food, they might keep on blaming themselves and feel like they are a failure and should just try harder. This can make them just fall deeper in the pit they are in, instead of getting the treatment they need.

I think the last part is not what you meant, but it sounded a bit that way.