Interesting that there is a flatpak build as well. I knew it was possible to run cli programs with flatpak but this the first programm i see that explicitly lists that as an option.

Warframe

Like literally pull my disk out of a gaming nvidia machine, and plug it into my AMD machine with full working graphics.

This should work already, i switched from nvidia to amd this year by swapping the cards and removing the nvidia drivers some time later.

I guess it’s because the drivers only apply to their specific hardware, so no problems having amd and nvidia drivers present at the same time.